ENGINEERED for the Scientific Race
High-quality meets efficiency to advance your research
IPA's advanced protein production workflows are customized to deliver a wide variety of conventional to complex recombinant proteins and antibody formats, including mono-, bi-, tri-, and multispecific antibodies, suitable for research and pre-clinical applications. Our efficient processes ensure accelerated turnaround times and exceptional results.
Quality. Efficiency. Flexibility.
• > 97 % purity*
• Low in endotoxin, < 1 EU/mg*
• High success rate, > 99 %
• > 9,000 programs
• > 3,000 projects
• 3 weeks turn-around time**
• High client retention
Cell Lines:
HEK293E
Expi293TM
ExpiCHO-STM
FreeStyleTM 293-F
*From consolidated historic data. **After gene delivery
Diverse Antibody Formats
• Full antibody
• VHH
• VNAR
• scFv
Species:
• Human
• Mouse
• Rabbit
• Llama
• Other
Isotype:
• IgG
• IgM
• IgA
• IgE
Specificity:
• Mono specific
• Bi-Specific
• Multi-specific
• Knob-in-hole
• cFAE
Versatile Protein Formats
Fusion protein:
• Fc
• GH
• MBP
• GST
Location:
• Secreted
• Intracellular
Tag:
• Untagged
• His
• Strep
• C-tag
• FLAG
Optional protease site:
• TEV
• Enterokinase
Solve your most complex recombinant protein production needs
Transient Protein Production Platform (rPEx®)
IPA's proprietary rPEx® platform offers a cutting-edge solution for producing fully post-translationally modified recombinant proteins and antibodies. Utilizing serum-free, suspension-growing HEK and CHO cells, transiently transfected with our proprietary expression vectors containing your gene of interest. The rPEx platform delivers products in less than 3 weeks after gene delivery with high purity and quality, featuring endotoxin levels below 1.0 EU/mg, whether you need just a few hundred micrograms or up to gram amounts of purified antibody or protein.
* average expression level 100 – 500 mg/L, depending on sequence
Bi- and Multispecific Protein Production
With over two decades of expertise in recombinant protein production, IPA excels in delivering high-quality biomolecules. Our cutting-edge rPEx-ms platform, featuring innovative knob-in-hole or duobody technologies, is designed for the efficient production of bi- and multispecific recombinant antibodies. From high-throughput discovery programs (10 – 100 µg) to automated medium-scale production projects (100 µg – 10 mg) and large-scale preparative batch productions (10 mg – 1 gram), IPA provides tailored solutions to meet your needs. Achieve superior quality bispecific antibodies that drive your research and development projects forward.
Fast turnaround, dedicated to quality, and optimized for maximum protein yields
Explore a solution crafted for you. With our innovative project strategy and unparalleled flexibility, we redefine excellence with a state-of-the-art lab in Europe shipping anywhere globally.
Overview
Expert protein production services customized to your needs
With over 22 years of experience and a strong record of client retention, IPA is your go-to partner in delivering high-quality recombinant protein expression and purification. Available as a standalone service or seamlessly integrated into antibody discovery projects, our expertise and commitment are focused on your success. Our dedicated team of protein scientists provides the precise protein tools you need, whether supporting pre-IND studies or enhancing your diagnostic kits.
Cutting-edge technology and flexible solutions
Utilizing the rPEX® platform with HEK and CHO cell lines, we ensure the highest quality, scalability, and stability in our manufactured products. Additionally, we offer the flexibility to work with your stable cell lines and hybridomas, providing customized solutions to meet your specific requirements.
Trending topics
Lead the way with IPA.
Trending topics
We have the longest memory
Rabbit monoclonal antibodies with B Cell Select® with Function-First from IPA are unmatched for early identification of a high affinity, highly specific antibodies.
Bispecifics & IPA
Bring us your scaffold and we can do the rest. With years of experience using a variety of bi- and multi-specific modalities, IPA has end-to-end capabilities and throughput to ensure selection and development of the most relevant therapeutic candidates.
Wet lab + in silico
with LENSai
LENSai in silico applications for radically informed decisions are designed to lend great cost and time efficiencies, as part of the IPA antibody discovery portfolio of service.