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Biotherapeutic
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Connect with IPA

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HUB of
Biotherapeutic
Intelligence™
See our latest upcoming event
Tell me moreto Events
 
Connect with IPA

Contact usto Contact
Follow us on LinkedInto LinkedIn

HUB of
Biotherapeutic
Intelligence™
See our latest upcoming event
Tell me moreto Events
 
Connect with IPA

Contact usto Contact
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Explore the latest state-of-the-art technologies

Protein Production

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ENGINEERED for the Scientific Race

Services

High-quality meets efficiency to advance your research

IPA's advanced protein production workflows are customized to deliver a wide variety of conventional to complex recombinant proteins and  antibody formats, including mono-, bi-, tri-, and multispecific antibodies, suitable for research and pre-clinical applications. Our efficient processes ensure accelerated turnaround times and exceptional results.

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Quality. Efficiency. Flexibility.

• > 97 % purity* 
• Low in endotoxin, < 1 EU/mg* 
• High success rate, > 99 %
• > 9,000 programs 
• > 3,000 projects
• 3 weeks turn-around time**
• High client retention

Cell Lines:

HEK293E

Expi293TM

ExpiCHO-STM

FreeStyleTM 293-F

 

*From consolidated historic data. **After gene delivery

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Diverse Antibody Formats

• Full antibody
• VHH
• VNAR
• scFv

Species:
• Human
• Mouse
• Rabbit
• Llama
• Other

Isotype:
• IgG
• IgM
• IgA
• IgE

Specificity:
• Mono specific
• Bi-Specific
• Multi-specific
• Knob-in-hole
• cFAE

transient-protein-production-rpex

Versatile Protein Formats

Fusion protein:
• Fc
• GH
• MBP
• GST

Location:
• Secreted
• Intracellular

Tag:
• Untagged
• His
• Strep
• C-tag
• FLAG

Optional protease site:
• TEV
• Enterokinase

 

Solve your most complex recombinant protein production needs

    Transient Protein Production Platform (rPEx®)

    Transient Protein Production Platform (rPEx®

    IPA's proprietary rPEx® platform offers a cutting-edge solution for producing fully post-translationally modified recombinant proteins and antibodies. Utilizing serum-free, suspension-growing HEK and CHO cells, transiently transfected with our proprietary expression vectors containing your gene of interest. The rPEx platform delivers products in less than 3 weeks after gene delivery with high purity and quality, featuring endotoxin levels below 1.0 EU/mg, whether you need just a few hundred micrograms or up to gram amounts of purified antibody or protein.

     

    * average expression level 100 – 500 mg/L, depending on sequence

    bi-specific-antibodies

    Bi- and Multispecific Protein Production

    With over two decades of expertise in recombinant protein production, IPA excels in delivering high-quality biomolecules. Our cutting-edge rPEx-ms platform, featuring innovative knob-in-hole or duobody technologies, is designed for the efficient production of bi- and multispecific recombinant antibodies. From high-throughput discovery programs (10 – 100 µg) to automated medium-scale production projects (100 µg – 10 mg) and large-scale preparative batch productions (10 mg – 1 gram), IPA provides tailored solutions to meet your needs. Achieve superior quality bispecific antibodies that drive your research and development projects forward.

    Fast turnaround, dedicated to quality, and optimized for maximum protein yields

    protein timeline-1
    Explore a solution crafted for you. With our innovative project strategy and unparalleled flexibility, we redefine excellence with a state-of-the-art lab in Europe shipping anywhere globally. 

     

     

    Overview

    Expert protein production services customized to your needs

    With over 22 years of experience and a strong record of client retention, IPA is your go-to partner in delivering high-quality recombinant protein expression and purification. Available as a standalone service or seamlessly integrated into antibody discovery projects, our expertise and commitment are focused on your success. Our dedicated team of protein scientists provides the precise protein tools you need, whether supporting pre-IND studies or enhancing your diagnostic kits.

    Cutting-edge technology and flexible solutions

    Utilizing the rPEX® platform with HEK and CHO cell lines, we ensure the highest quality, scalability, and stability in our manufactured products. Additionally, we offer the flexibility to work with your stable cell lines and hybridomas, providing customized solutions to meet your specific requirements.

     

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